Precision and Perseverance: Tumor-Targeted Gene Editing Quest

Zhu, Yunxin Avery

Faculty of Science

Department of Applied Biology and Chemical Technology

In the year of 2022, Avery Zhu embarked on a thrilling scientific quest with a project titled “pH-Responsive Peptide for Tumor Targeted Delivery of CRISPR-Cas9 Ribonucleoprotein. Guided by the brilliant Prof. Clarence Wong, he dove into the fascinating world of gene editing. The mission was to harness the power of pH-responsive peptides to deliver CRISPR/Cas9 into cancer cells, a task that proved to be as daunting as it was exciting. The greatest challenge lay in producing uncontaminated RNA, necessitating the creation of a sustainable manufacturing line. After six months of persistent trial and error, she finally triumphed. The unwavering support from Avery’s mentors and peers was essential, and the project culminated in a top-grade thesis. This journey not only expanded her scientific expertise but also strengthened her resilience and patience.

Critical Thinking and Problem-solving

Networking and Collaboration

Adaptability and Flexibility

Continuous Improvement and Learning from Mistakes

2025-04

BSc(Hons) Applied Biology with Biotechnology

Undergraduate

Peptides -- Therapeutic use

CRISPR-associated protein 9

Gene editing

All rights reserved

English

Feature Story

open access