Molecular Mastery: Greener Medicine Manufacturing


Title

Molecular Mastery: Greener Medicine Manufacturing

Creator

Chung, Wai Hin Brian

Advisor

Yu, Wing Yiu Michael
Cheung, Kwong Chak Gary
Au, Chi Ming David

Faculty

Faculty of Science

Department

Department of Applied Biology and Chemical Technology

Description

Brian’s research at PolyU led to a breakthrough in synthesizing oxy-γ-lactams, vital for pharmaceuticals. By developing a copper-catalyzed method, his team reduced a multi-step process to a single efficient reaction, saving time and resources. This innovation offers precise control over molecular structure, enhancing drug effectiveness and sustainability in manufacturing. Overcoming challenges in atom arrangement, Brian learned to systematically optimize reactions and became meticulous in lab safety. Support from mentors and advanced facilities fueled his progress. Through this project, Brian gained technical expertise, problem-solving skills, and confidence in explaining complex chemistry, all while contributing to more accessible and eco-friendly medicines.

Learning outcome/goal

Critical Thinking and Problem-solving
Project Management and Teamwork
Adaptability and Flexibility
Communication and Presentation Skills
Reflection and Self-awareness

Date

2025-12

Programme

PhD

Degree Level

Postgraduate

Keywords

Organic Synthesis ; Stereochemistry ; Reaction Mechanism Investigation ; Nuclear Magnetic Resonance ; Green Chemistry

Subject

Organic compounds -- Synthesis
Catalysis
Pharmaceutical chemistry
Green chemistry

Rights

All rights reserved

Language

English

Type

Feature Story

Access Rights

open access