Brian’s research at PolyU led to a breakthrough in synthesizing oxy-γ-lactams, vital for pharmaceuticals. By developing a copper-catalyzed method, his team reduced a multi-step process to a single efficient reaction, saving time and resources. This innovation offers precise control over molecular structure, enhancing drug effectiveness and sustainability in manufacturing. Overcoming challenges in atom arrangement, Brian learned to systematically optimize reactions and became meticulous in lab safety. Support from mentors and advanced facilities fueled his progress. Through this project, Brian gained technical expertise, problem-solving skills, and confidence in explaining complex chemistry, all while contributing to more accessible and eco-friendly medicines.