Unlocking Molecular Mysteries: Journey in Organic Cage Synthesis

 

Yufei GE embarked on a challenging project to synthesize organic cages, unique structures with enzyme-like properties that could revolutionize chemical reactions. Despite initial setbacks, including unexpected side products, Yufei persevered. She meticulously analyzed NMR data, refining her methods with insights from literature and guidance from mentors like Prof. Raymond WONG and Dr. Gary CHEUNG.

Over three intense months, Yufei mastered new techniques, from GPC purification to 2D NMR analysis. Her dedication not only earned her a prestigious leadership award but also paved the way for more affordable industrial chemical processes, showcasing her commitment to innovation and excellence in the field.

 


FS student

Ms. GE Yufei

Department of Applied Biology and Chemical Technology
Faculty of Science

Award:

  • Presidential Student Leadership Award of the Department 2023, The Hong Kong Polytechnic University

 

Domain Expertise:

Synthesis of Organic Cages

This involves creating complex molecular structures with a defined cavity, which can mimic enzyme-like behavior by selectively binding reagents. The synthesis process requires understanding organic chemistry principles, including reaction mechanisms and the ability to design synthetic routes for assembling molecular fragments.

Photochemical Mechanisms

This area focuses on studying how light interacts with materials that can donate or accept electrons. Understanding these mechanisms is crucial for developing materials with specific electronic properties, which can be applied in fields like photovoltaics and photodetectors.

Nuclear Magnetic Resonance

NMR is a powerful analytical technique used to determine the structure of organic compounds. Proficiency in 2D NMR analysis allows researchers to identify complex molecular structures, such as organic cages, by interpreting the interactions between atomic nuclei in a magnetic field.

Gel Permeation Chromatography

GPC is a technique used to separate and purify polymers and large molecules based on their size. Mastery of GPC is essential for purifying synthesized organic cages, ensuring that the final product is free from impurities and side products.

 

Lifelong Learning Excellence:

Critical Thinking and Problem-solving

This skill involves identifying challenges, analyzing potential causes, and developing effective solutions. In the project, problem-solving was crucial when reactions didn't proceed as expected. By consulting literature and revising experimental steps, the ability to troubleshoot and adapt was honed, which is valuable in any field or situation.

Project Management and Teamwork

Managing time effectively was essential during the three-month project. Planning experiments and estimating their duration helped avoid delays. This skill is vital for balancing multiple tasks and responsibilities, ensuring productivity and meeting deadlines in both professional and personal contexts.

Networking and Collaboration

Working collaboratively with others was recognized through the Presidential Student Leadership Award. Effective collaboration involves communication, respect, and leveraging diverse skills within a team to achieve common goals. This skill is crucial in any environment where teamwork is required.

Adaptability and Flexibility

The project required adapting to new techniques, such as operating a GPC machine and analyzing 2D NMR data. Being open to learning and quickly acquiring new skills is essential in a rapidly changing world, allowing individuals to stay relevant and excel in various situations.

 


Inspiring Quotes:



Explore More:

The pursuit of knowledge is a lifelong journey! To further expand your knowledge and continue your personal and professional growth. Click and explore the following learning resources:

Domain Knowledge OER

Synthesis of Organic Cages

Photochemical Mechanisms

Nuclear Magnetic Resonance

Gel Permeation Chromatography

Lifelong Learning OER

Critical Thinking and Problem-solving

Project Management and Teamwork

Networking and Collaboration

Adaptability and Flexibility